ATG™ CodonXpert Codon Optimization Tool

Genetic code’s degeneracy enables multiple DNA sequences to encode the same protein, but this variability influences the efficiency of heterologous protein production due to codon usage preferences unique to each organism. Codon optimization, the process of adjusting synonymous codons to match an organism’s preferences, must account for local sequence patterns beyond general codon biases. This creates a vast combinatorial search space that cannot be exhaustively explored. However, the diversity of life on Earth, shaped by natural selection, offers a wealth of optimized sequences that AI algorithms can leverage to uncover the underlying rules governing codon usage.

Introducing ATG™ CodonXpert

Introducing ATG™ CodonXpert, the premier AI-assisted codon optimization tool designed to revolutionize gene synthesis and protein expression across diverse organisms.

Unlock the Power of Genetic Engineering with Precision Optimization

Why Choose ATG™ CodonXpert?

ATG™ CodonXpert employs advanced AI architectures to optimize DNA/RNA & protein sequences, ensuring enhanced protein expression, stability, and efficiency tailored to your specific host organism.

Key Features:

• Global & Temporal Codon Pattern Recognition
  ATG™ CodonXpert captures naturally occurring codon patterns across various species and temporal phases, ensuring accurate and efficient translation.
• Optimized Translation & Folding Balance
  Achieve seamless synchronization between codon usage and protein folding, minimizing misfolding and maximizing functional protein yield.
• Secondary Structure Elimination
  Prevent detrimental secondary structures that hinder transcription and translation, ensuring smooth gene expression.
• Internal Sequence Removal
  Automatically detects and removes unwanted internal sequences, such as ribosome entry sites, preventing premature translation initiation and ensuring proper protein synthesis.
• Enhanced mRNA Stability
  ATG™ CodonXpert optimizes codon usage to enhance mRNA stability, extending the half-life of your transcripts for prolonged and efficient protein production.
• Multi-Factorial Optimization
  Benefit from comprehensive optimization based on GC content and codon pair preferences, ensuring maximal gene expression and minimal toxicity.

Experience the Future of Codon Optimization

With ATG™ CodonXpert, gene synthesis becomes faster, smarter, and more efficient, empowering researchers and biotech companies to unlock new frontiers in genetic engineering.